Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation

ChEBI2011-12-01 更新2026-07-21 收录

T细胞免疫调节

BMP信号通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-27378 数据链接链接失效反馈

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Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation

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2011-12-01

The BMP Ligand Gdf6 Prevents Differentiation of Coronal Suture Mesenchyme in Early Cranial Development

颅缝发育分子机制

BMP信号通路

Growth Differentiation Factor-6 (Gdf6) is a member of the Bone Morphogenetic Protein (BMP) family of secreted signaling molecules. Previous studies have shown that Gdf6 plays a role in formation of a

NIAID Data Ecosystem70

Transcriptome analysis of antigen-specific T follicular helper (Tfh) and non-Tfh cells after Bach2 overexpression. Transcriptome analysis of antigen-specific T follicular helper (Tfh) and non-Tfh cells after Bach2 overexpression

T细胞免疫调节

转录组学分析

We identified Bach2 as factor to be expressed at low levels in Tfh cells. Induced overexpression of Bach2 in the germinal center reaction results in loss of the Tfh cell population. RNA-seq of sorted

NIAID Data Ecosystem40

bHLH transcription factor ATOH8 overexpression effect on endothelial cells: gain-of-function model [GOF]. bHLH transcription factor ATOH8 overexpression effect on endothelial cells: gain-of-function model [GOF]

内皮细胞ATOH8功能

BMP信号通路

Analysis of human umbilical vein endothelial cells (HUVECs) adenovirally expressing the transcription factor ATOH8. Overall design: ATOH8 was identified as a direct target gene of BMP-9/ALK-1/SMAD sig

NIAID Data Ecosystem40

Role of interleukin 2 on Foxp3+CD4+ regulatory T (Treg) cell gene expression and chromatin modeling in thymus and lymph node, and on SATB1 DNA binding in single positive CD4 thymocytes

T细胞免疫调节

表观基因组学

Interleukine 2 (IL-2) is still one of the most interesting cytokines in T cell biology with its ability to control immune homeostasis by maintaining the functional identity of Foxp3+ regulatory T (Tre

NIAID Data Ecosystem40

Control Mint-ChIP-seq from activated T-cell (ENCSR897COL)

表观遗传学分析

T细胞免疫调节

Control Mint-ChIP-seq on activated T-cell male adult (38 years) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENC

NIAID Data Ecosystem40

Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation

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