Transcripts identified by microarray analysis that were deregulated in E14.5 Tbx18(cre/+);FGFR1(fl/fl);FGFR2(fl/fl) (Fgfr1/2cDKO) ureters

Evaluation of the transcriptional changes in E14.5 ureters upon loss of Fgfr1 and Fgfr2 in the ureteric mesenchyme. Total RNA from dissected ureters of E14.5 Fgfr1/2cDKO and control embryos was analyzed by microarray analysis.本研究针对输尿管间充质（ureteric mesenchyme）中Fgfr1与Fgfr2缺失后，胚胎发育第14.5天（E14.5）输尿管的转录组变化展开评估。研究人员对从E14.5天Fgfr1/2条件性双敲除（Fgfr1/2cDKO）胚胎与对照胚胎中解剖分离的输尿管所提取的总RNA，采用微阵列分析（microarray）进行了检测分析。