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Enantioselective Synthesis of Dihydropyran-Fused Indoles through [4+2] Cycloaddition between Allenoates and 3‑Olefinic Oxindoles

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NIAID Data Ecosystem2026-03-08 收录
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https://figshare.com/articles/dataset/Enantioselective_Synthesis_of_Dihydropyran_Fused_Indoles_through_4_2_Cycloaddition_between_Allenoates_and_3_Olefinic_Oxindoles/2166298
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A highly enantioselective [4+2] annulation with respect to allenoates and 3-olefinic oxindoles catalyzed by Lewis base was reported, which proved to be an efficient way to synthesize chiral dihydropyran-fused indoles. The cycloaddition products were generally obtained in high yields (up to 98%) with very good enantioselectivities (up to 94% enantiomeric excess).
创建时间:
2016-02-13
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