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Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC8158

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Protein Data Bank Japan2023-09-27 更新2026-04-04 收录
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Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC8158 Descriptor: 5'-S-(4-{[(4'-chloro[1,1'-biphenyl]-3-yl)methyl]amino}butyl)-5'-thioadenosine, ETHANOL, POTASSIUM ION, ... Authors: Kottur, J, Aggarwal, A.K. Deposit date: 2023-01-07 Release date: 2023-07-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. Plos Pathog., 19, 2023
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2023-01-07
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