FoxK1 Associated Gene Regulatory Network in Hepatic Insulin Action and It’s Relationship to FoxO and Insulin Receptor Mediated Transcriptional Regulation. FoxK1 Associated Gene Regulatory Network in Hepatic Insulin Action and It’s Relationship to FoxO and Insulin Receptor Mediated Transcriptional Regulation

ChIP-seq analysis demonstrates FoxK1 binding to proximal promoters and enhancers, especially to genes containing a TGTTTAC motif, which is similar to the FoxA/FoxO motifs. Overall design: Examination of FoxK1 binding in basal and insulin-stimulated HepG2 cells (ChIP-seq).