Three-Component Assembly of Conjugated Enyne Scaffolds via E-Selective Olefination of Ynals
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Benefited by the accessible ynamido–lithium intermediates Ib from a Cu-catalyzed azide–alkyne cycloaddition in the presence of stoichiometric amounts of LiOH, a mild and flexible three-component route to conjugated enyne scaffolds was successfully achieved via a formal E-selective olefination strategy.
创建时间:
2016-02-20



