Association between TLR4 SNPs and LOAD risk.

All models were adjusted for age, gender, education, and ApoE e4 status.Abbreviations: LOAD, late-onset Alzheimer's disease; AOR, adjusted odds ratio; CI, confidence interval; SNP, single nucleotide polymorphism.#0 copies, wild type; 1 copy, heterozygotes; 2 copies, homozygous variants.Numbers in bold indicates statistically significant findings (pAdditive model is assessing the association between number of variant allele and LOAD.*The result remained significant (2 copies of variant SNP3, p = 0.004) after controlling for type I error by using Bonferroni correction (α = 0.05/5).