five

Transcriptome characterization of radiation-induced sarcomas

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE102055
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We performed RNA sequencing on secondary sarcomas, arising from previous radiation therapies. We investigated whether such radiation-induced tumours harbour specific genomic and/or transcriptomic alterations compared to sporadic (primary) sarcomas. We compared 77 radiation-induced (secondary) sarcomas to 93 sporadic (primary) sarcomas. Transcriptome is studied by RNA-seq (Illumina) and genome is studied by array-CGH (Affymetrix SNP6 and CytoScan HD) plus gene fusions identified using RNA-seq.
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2019-06-28
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