Cloning and Expression of Class A β-Lactamase Gene blaA(BPS) in Burkholderia pseudomallei

Name: Cloning and Expression of Class A β-Lactamase Gene blaA(BPS) in Burkholderia pseudomallei
Creator: American Society for Microbiology (ASM)
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PubMed Central2026-05-16 收录

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https://pmc.ncbi.nlm.nih.gov/articles/PMC127091/

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The β-lactamase gene blaA(BPS) in Burkholderia pseudomallei was cloned and expressed in Escherichia coli. BPS-1 is a cephalosporinase with an isoelectric point of 7.7. Sequence analysis of BPS-1 revealed conserved motifs typical of class A β-lactamases and a relationship to the PenA (in B. cepacia) and BlaI (in Yersinia enterocolitica) lineages.

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American Society for Microbiology (ASM)