Additional file 8 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7

Additional file 8. Ingenuity Pathways Analysis (IPA) of DEGs specific to the AP, by comparison with two or more of the other (UM, UC-M, and/or UC-F) models. (.xlsx). Significantly enriched: (A) Pathway and (B) Disease-related GO terms are shown, with the p-value and the DEGs from which each term was derived. (C-G) All genes with differential expression between the AP and the three other models (gene list in C: comparison to UM, UC-M, UC-F) were compared with genes (D-E) that were significant in a transcription-wide association study (TWAS) of autism or that (F-G) had genome-wide significance for de novo protein-coding variants associated with neurodevelopmental disorders, as described in the results text. n = 4; data values are in Additional file 5.