Rat iPS F65 cells' gene expression difference compared with that of the adult cells including rat BMC and PEF cells

Rat iPS F65 cells had different gene expression level compared with that of the adult cells including rat bone marrow cells(BMC) and rat primary ear fibroblasts(PEF). This difference gave rat iPS F65 cells unique characteristics which could then be compared with other species' ES cells or iPS cells like human ES cells and mouse ES cells by the homologue genes comparison to show which species' ES cells or iPS cells were more competitive with the other.大鼠iPS F65细胞（induced pluripotent stem cells, iPS）与包括大鼠骨髓细胞（bone marrow cells, BMC）及大鼠原代耳成纤维细胞（primary ear fibroblasts, PEF）在内的成体细胞的基因表达水平存在差异。该差异赋予大鼠iPS F65细胞独特的细胞特性，后续可通过同源基因（homologous genes）比对，将其与其他物种的胚胎干细胞（embryonic stem cells, ES）及iPS细胞（如人胚胎干细胞、小鼠胚胎干细胞）进行比较，以明确何种物种的ES细胞或iPS细胞更具竞争优势。