Additional file 1 of Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains

Additional file 1 : Supplementary Table 1. Demographic and sample information of all 51 patients analyzed. Supplementary Table 2. Demographic and sample information of group of 40 paired, 9 unpaired. *Donor tissue used for snRNA-seq. Supplementary Table 3. GREAT analysis of Top 5000 differential sites for Level 1 analysis. Supplementary Table 4. HOMER Motif search result of top 5000 sites more accessible in neuron and non-neuron. Supplementary Table 5. Demographic information for bulk ATAC-seq tissue samples. Supplementary Table 6. Differential analysis of Whole tissue vs neuron/non-neuron mixed. Terms in blue represent association with glial function and the ones in red represent association with neuronal function. Terms in green represent association with general brain function. GO terms enriched in DE sites of non-neuron vs whole tissue. Supplementary Table 7. GO terms enriched in DE sites of neuron vs whole tissue. Supplementary Table 8. GO terms enriched in sites more accessible in mixed neuron/non-neuron vs whole tissue. Supplementary Table 9. GO term enrichment of LOAD down differential sties in female glia controls vs. cases, FDR