Evaluating developmental effects of Tmem184b in dorsal root ganglia

We evaluated transcriptomic signatures at critical timepoints of sensory differentiation in wild type and Tmem184b mutant mice. Wild type control C57BL/6 and Tmem184b gene-trap mutant mice (n=3-4 per timepoint and genotype) were evaluated at E13, P0, and P10我们针对野生型与Tmem184b突变小鼠感觉分化的关键时间点，对其转录组特征（transcriptomic signatures）开展了评估。本研究以野生型对照C57BL/6小鼠及Tmem184b基因陷阱（gene-trap）突变小鼠为实验材料，分别在胚胎第13天（E13）、出生后第0天（P0）与出生后第10天（P10）三个时间点进行检测，每个时间点及对应基因型的生物学重复样本量为3-4例。