Lnc-SLC15A1-1 Up-regulates CXCL10/CXCL8 Expression in Endothelial Cells by Sponging MicroRNAs
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE185363
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The molecular factors that cause disproportional increase in CVD in the DM/chronic kidney disease (CKD) population are still unknown. HUVESs were treated with high glucose (HG) or HG superimposed uremic toxin indoxyl sulfate (IS). Lnc-SLC15A1-1 was significant different expression between these two condition. HUVECs were transfected with lnc-SLC15A1-1 overexpression vector then microarray was applied to evaluate the downstream regulated gene. HUVECs were transfected with a lnc-SLC15A1-1 expression plasmid (pcDNA3.1(+)-lnc-SLC15A1-1) or empty vector (EV) as a control by employing the TransIT-X2 delivery system
创建时间：
2022-01-06
