Transcription profiling of skeletal muscle from wild type and Nebulin knock-out mice

Knock out of the Nebulin gene. We compared the Quadriceps of two Nebulin -deficient vs. 2 Wildtype mice. The two KO-WT pairs derived from two litters (F2 generation, background: C57/Bl6 and 129/IB10).针对伴肌动蛋白（Nebulin）基因开展敲除操作。我们对比了2株伴肌动蛋白缺陷型小鼠与2株野生型（Wildtype）小鼠的股四头肌（Quadriceps）组织。这2组敲除型（KO）-野生型（WT）配对样本均来源于2个产仔窝，均为F2代，遗传背景为C57/Bl6及129/IB10品系。