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Expression data of organoid derived from HSCs

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE121298
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To investigate the differences in mRNA expression profiles between TSG-6 or vehicle treated Hu-pHSCs and BM-MSCs organoid spheroids, we performed mRNA microarrays for total RNA extracts isolated from these spheroids (vehicle: CON/3D=3, TSG6: TSG-6/3D=4, BM: BM-MSCs3D=3) We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process. For profiling, we established organoid spheroid as described previously hepatic organoid culture methods.
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2021-10-19
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