Farnesyl transferase structure of Jansen compound
收藏Protein Data Bank Japan2024-02-14 更新2026-03-21 收录
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https://pdbj.org/mine/summary/1x81
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Farnesyl transferase structure of Jansen compound Descriptor: 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ... Authors: Li, Q, Claiborne, A, Li, T, Hasvold, L, Stoll, V.S, Muchmore, S, Jakob, C.G, Gu, W, Cohen, J, Hutchins, C, Frost, D, Rosenberg, S.H, Sham, H.L. Deposit date: 2004-08-16 Release date: 2004-12-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors. Bioorg.Med.Chem.Lett., 14, 2004
创建时间：
2004-08-16
