Simulations of cochlear nucleus bushy cells reconstructed from serial blockface electron microscopy (V1.0)

This repository contains simulation results based on biophysical representations of mouse ventral cochlear nucleus bushy cells reconstructed in 3D from serial blockface (volume) electron microscopy. Included in the dataset are the morphology files for use in NEURON (complete reconstructions in SWC format; original and manipulated reconstructions in .hoc format), and simulation result files in Python pickle format. Data are included for 10 fully-reconstructed cells.The software and documentation used to generate the simulations (and use the morphology files) can be found on GitHub (see References below).NOTE: This dataset is an early version of the dataset associated with the final paper from this work. Please refer to the dataset listed below.Spirou GA, Kersting M, Carr S, Razzaq B, Yamamoto Alves Pinto C, Dawson M, Ellisman MH, Manis PB. High-resolution volumetric imaging constrains compartmental models to explore synaptic integration and temporal processing by cochlear nucleus globular bushy cells. Elife. 2023 Jun 8;12:e83393. doi:10.7554/eLife.83393. PMID: 37288824; PMCID: PMC10435236.The final dataset can be found on Dryad: https://datadryad.org/dataset/doi:10.5061/dryad.4j0zpc8g1<br><br>