Collaborative Cohort of Cohorts for COVID-19 Research (C4R): Genetic Epidemiology of COPD Study (COPDGene)

<u>**Cohort Description**</u> <br>The Genetic Epidemiology of COPD (COPDGene) study is a non-interventional, multicenter, longitudinal, case-control study at 21 US sites of smokers with a &#8805;10 pack-year history of smoking, with and without COPD, and healthy never smokers. The initial goal was to characterize disease-related phenotypes and explore associations with susceptibility genes.

<u>**Data Being Submitted**</u> <br>Wave 1 questionnaire data includes 397 variables for up to 3683 COPDGene participants in C4R. <br>Wave 2 questionnaire data includes 447 variables for up to 2191 COPDGene participants in C4R. <br>Dried Blood Spot/Serosurvey data includes 7 variables for up to 1692 COPDGene participants in C4R. <br>Derived data includes 43 variables for up to 4082 COPDGene participants in C4R. <br>Phenotype data includes 113 variables for up to 4082 COPDGene participants in C4R.