Propagation of Adipogenic Signals through an Epigenomic Transition State

ChEBI2010-05-20 更新2026-07-21 收录

脂肪生成

表观遗传

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21898 数据链接链接失效反馈

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Propagation of Adipogenic Signals through an Epigenomic Transition State

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2010-05-20

Bioorthogonal Chemical Epigenetic Modifiers Enable Dose-Dependent CRISPR Targeted Gene Activation in Mammalian Cells

基因调控

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CRISPR-Cas9 systems have been developed to regulate gene expression by using either fusions to epigenetic regulators or, more recently, through the use of chemically mediated strategies. These approac

NIAID Data Ecosystem80

NG Capture-C analysis of GADD45a-bound adipogenic super-enhancers

染色质构象

脂肪生成

ING1b and GADD45a are nuclear proteins involved in the regulation of cell growth, apoptosis and DNA repair. We previously found that ING1b is essential to target GADD45a-mediated active DNA-demethylat

NIAID Data Ecosystem70

Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome.

转录调控

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The conserved core domain of the TATA binding protein (TBP) interacts with multiple partners forming the complexes required for transcription by RNA Polymerases I, II and III. We use genetically modif

NIAID Data Ecosystem50

8p H3K27me3 Part 2

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X染色体失活

Green is RNA FISH using a probe against XIST RNA. Red is an anti-H3K27me3 antibody. Blue is DAPI. These images were used to calculate data shown in Table 2.

Figshare2016-01-20 更新80

Whole-genome DNA methylation maps for human and chimpanzee peripheral blood leukocytes (PBLs).

跨物种DNA甲基化分析

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It has been thought that epigenetic changes underlie the evolutionary divergence of phenotype between closely related species. To study differences in DNA methylation between humans and chimanzees, we

NIAID Data Ecosystem50

Propagation of Adipogenic Signals through an Epigenomic Transition State

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