Eml1
收藏rgd.mcw.edu2025-01-21 收录
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1314955
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资源简介：
Enables microtubule binding activity. Involved in brain development; mitotic spindle organization; and neuroblast proliferation. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in cytosol. Colocalizes with mitotic spindle midzone and mitotic spindle pole. Is expressed in liver; lung; nervous system; and retina. Used to study congenital nervous system abnormality and subcortical band heterotopia. Human ortholog(s) of this gene implicated in subcortical band heterotopia. Orthologous to human EML1 (EMAP like 1). [provided by Alliance of Genome Resources, Nov 2024]
该基因激活微管结合活性，参与大脑发育、有丝分裂纺锤体组织以及神经母细胞增殖。在造血祖细胞分化过程中，位于细胞质中，并与有丝分裂纺锤体中区和纺锤体极共定位。在肝脏、肺部、神经系统以及视网膜中表达。用于研究先天性神经系统异常和皮质下带异位。该基因的人类同源基因与皮质下带异位有关。与人类EML1（EMAP样1）同源。[由基因组资源联盟提供，2024年11月]
提供机构：
Rat Genome Database
