Transition-Metal-Free Approach to Polysubstituted Furans
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https://figshare.com/articles/dataset/Transition-Metal-Free_Approach_to_Polysubstituted_Furans/11714421
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A convenient and straightforward strategy for the synthesis of 2,3-disubstituted and 2,3,5-trisubstituted furans via a base-promoted domino reaction of β-keto compounds with vinyl dichlorides is described. This transition-metal-free approach proceeds under operationally simple reaction conditions featuring easily available starting materials, a broad substrate scope, and good functional group tolerance.
创建时间:
2020-01-16



