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Proline-Catalyzed Asymmetric Synthesis of syn- and anti-1,3-Diamines

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Figshare2016-02-18 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Proline_Catalyzed_Asymmetric_Synthesis_of_i_syn_i_and_i_anti_i_1_3_Diamines/2345821
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A general organocatalytic strategy for asymmetric synthesis of both syn/anti-1,3-diamines has been developed. The strategy employs proline-catalyzed sequential α-amination and Horner–Wadsworth–Emmons (HWE) olefination of aldehydes as the key step where syn-1,3-diamine was obtained as the most favorable product.
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2016-02-18
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