Crystal structure of CARM1 in complex with inhibitor WH5C
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Crystal structure of CARM1 in complex with inhibitor WH5C Descriptor: (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(5-carbamimidamidopentyl)amino]-2-azanyl-butanoic acid, GLYCEROL, Histone-arginine methyltransferase CARM1 Authors: Gunnell, E.A, Muhsen, U, Dowden, J, Dreveny, I. Deposit date: 2019-07-04 Release date: 2020-03-04 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.062 Å) Cite: Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4). Biochem.J., 477, 2020
创建时间:
2019-07-04



