Effects of Retinoic Acid on mTOR, SAMHD1 and TCF4 Expression in Macrophages

Monocyte-derived macrophages (MDMs) were generated from monocytes of HIV-uninfected individuals in the presence or the absence of all trans retinoic acid (ATRA). MDMs were tested by western blotting for the expression of mTOR, S6K, and SAMHD1 protein expression/phosphorylation, as well as TCF4 protein expression.

This file is linked to the manuscript entitled "Retinoic Acid Boosts HIV-1 Replication in Macrophages via CCR5/SAMHD1-Dependent and mTOR-Modulated Mechanisms" by Jonathan Dias, Petronela Ancuta et al., submitted for publication October 5th, 2023 (reprint available on www.BioRxiv.org)