BIOGRID CURATED DATA FOR LEO1 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for LEO1 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Component of the Paf1 complex; which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay

蛋白质-蛋白质、遗传以及化学相互作用数据集，针对酵母菌（Saccharomyces cerevisiae S288c）中的LEO1进行整理，由BioGRID（https://thebiogrid.org）维护；定义：Paf1复合体的组成部分；与RNA聚合酶II结合，参与组蛋白甲基化；在调节Ty1转座中发挥作用；通过基于G缺失的运行（GLRO）试验证实其在转录延伸过程中的作用。