Group differences based on diagnosis and remission status

MMSE = mini-mental state exam; MADRS = Montgomery-Asberg Depression Rating Scale. All measures presented as mean (standard deviation), except sex. All volumes presented in milliliters. Differences between groups tested using analysis of covariance (ANCOVA), except for sex, which used the chi square test. Age of onset data were examined using two-tailed pooled t-tests and MADRS data using a Satterthwaite t-test due to unequal variances. Age of onset and MADRS data were only available for the depressed population.