Baseline characteristics of patients and of HCs and study drug exposure and compliance throughout the study.

aFor the difference between groups from the Student’s t-test.
bFor the difference between groups from Fisher’s exact test.
cIncludes one of Hispanic ethnicity, all other subjects were not Hispanic.
dPatients reported the same number of relapses for the past 24 months.
eCompliance was calculated at study visits using subject diaries and returned drug. Exposure was calculated from compliance.
BMI; body mass index; DMD, disease-modifying drug; EDSS, Expanded Disability Status Scale; HC, healthy control; IFN β-1a, interferon beta-1a; IV Ig, intravenous immunoglobulin; MS, multiple sclerosis; SC, subcutaneous; SD, standard deviation; tiw, three times weekly.