Cathepsin D (CD) plays an important role in both biological and pathological processes, although the cleavage characteristics and substrate selection of CD have yet to be fully explored. We employed l

Figshare2016-01-18 更新80

Substrate specificity of fusolisin.

蛋白酶底物特异性

质谱肽段分析

A) Major peptides obtained by fusolisin hydrolysis of fibrinogen. B) Major peptides obtained by fusolisin hydrolysis of FRETS-25 Thr. D-A2pr(Nma)- Gly- [Phe/Ala/Val/Glu/Arg] - [Pro/Tyr/Lys/Ile/Asp]- T

NIAID Data Ecosystem50

File S1 - Oligosaccharide Substrate Preferences of Human Extracellular Sulfatase Sulf2 Using Liquid Chromatography-Mass Spectrometry Based Glycomics Approaches

糖组学

蛋白酶底物特异性

Contains the following files: Figure S1. Normalized decreases for each HS composition assuming one sulfate removal turnover by HSulf2 from Fig. 1. A. DP6 Oligosaccharides, B, DP8 oligosaccharides. Fig

NIAID Data Ecosystem100

Alanine scanning mutagenesis of the NS3/4A cleavage sequences.

蛋白酶底物特异性

HCV多蛋白加工

Alanine scanning mutagenesis was used to systematically substitute amino acid residues at the P6–P4′ positions of the NS3-NS4A (1652DLEVVT↓STWV1661), NS4A-NS4B (1706DEMEEC↓SQHL1715), NS4B-NS5A (1967EC

NIAID Data Ecosystem60

Factor Xa PICS with chymotryptic peptide library

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