Crystal structure of anaplastic lymphoma kinase (ALK) bound by Brigatinib
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Crystal structure of anaplastic lymphoma kinase (ALK) bound by Brigatinib Descriptor: 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor Authors: Dougan, D.R, Zhou, T. Deposit date: 2018-10-30 Release date: 2018-12-12 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase. J. Med. Chem., 59, 2016
创建时间：
2018-10-30
