Gene expression analysis after miR-125a-3p over-expression in oligodendrocyte precursor cells (OPCs). Gene expression analysis after miR-125a-3p over-expression in oligodendrocyte precursor cells (OPCs)

MiR-125a-3p over-expression in OPCs impairs their differentiation into fully mature oligodendrocytes. We performed a whole microarray profiling to identify new miR-125a-3p direct targets and altered signaling pathways responsible for its the detrimental effect on oligodendrocyte maturation. Overall design: Gene expression was measured in OPCs 48h after miR-125a-3p (or negative control) over-expression. 2 indipendent samples were used for each condition.