Serum amino acids profile with arginine or glutamine supplementation in DSS-induced colitis model.

Arginine availability index (AAI)  = serum [L-Arg]/([L-Orn] + [L-Lys])
DS 0.38±0.02b 0.35±0.04b
DS+Arg 0.52±0.03a 0.64±0.06a
DS+Gln 0.57±0.05a 0.59±0.03a
At day 7, serum amino acids profile in mice treated with DSS feeding basal diet (DS), or 1.5% arginine supplementation (DS+Arg), or 2.0% arginine supplementation (DS+Gln), were detected. At day 12, serum amino acids profile in mice treated with DSS feeding basal diet (DS), or 0.4% arginine supplementation (DS+Arg), or 0.5% glutamine supplementation at day 12 (DS+Gln), were detected. Data are presented as mean ±SEM, n = 6, with a-c used to indicate a statistically significant difference (P<0.05, one way ANOVA method).