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Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis

NIAID Data Ecosystem2026-05-26 收录

神经退行性分子机制

时空转录组学

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP162456 数据链接链接失效反馈

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资源简介：

Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis Overall design: 4 timepoints in SOD1-G93A model with WT control; 2 timepoints in ATG7 model

应用场景：

创建时间：

2019-04-05

衰老相关蛋白

神经退行性分子机制

The attachment of Post-Translational Modifications (PTMs) to proteins plays key roles in the regulation of the activity and stability of various proteins. Here we utilized the nematode Caenorhabditis

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Data Sheet 6_Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin.pdf

神经退行性分子机制

tau蛋白相互作用

IntroductionRNA expression is modulated by tau. We used two mouse models, THY-Tau22 mice, which express pro-aggregation tau, and TauKO mice, which are null for tau, to improve our understanding of tau

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Code for: Robust transcriptional indicators of plant immune cell death reveal...

植物免疫细胞死亡

时空转录组学

This dataset compiles the code for the research article "Robust transcriptional indicators of plant immune cell death revealed by spatio-temporal transcriptome analyses",...

B2FIND00

Global gene profiling of (-)-Epigallocatechin-3-gallate (EGCG)-induced neuronal death. Mus musculus

神经退行性分子机制

药物神经保护

Alzheimer’s disease (AD) is the most common form of adult-onset dementia with severe intellectual deterioration and is characterised by the accumulation of the amyloid-β (Aβ) peptides and the presence

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Multimodal spatiotemporal transcriptomic resolution of embryonic palate osteogenesis [multiome RNAseq+ATACseq]

胚胎腭部骨生成

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The terminal differentiation of osteoblasts and subsequent formation of bone marks an important phase in palate development that leads to the separation of the oral and nasal cavities. While the morph

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Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis

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