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Crystal Structure of Rat Vitamin D Receptor Ligand Binding Domain Complexed with VitIII 17-20Z and the NR2 Box of DRIP 205

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Crystal Structure of Rat Vitamin D Receptor Ligand Binding Domain Complexed with VitIII 17-20Z and the NR2 Box of DRIP 205 Descriptor: (1R,3R,7E,17Z)-17-(5-hydroxy-1,5-dimethylhexylidene)-2-methylene-9,10-secoestra-5,7-diene-1,3-diol, Peroxisome proliferator-activated receptor-binding protein, Vitamin D3 receptor Authors: Vanhooke, J.L, Benning, M.M, DeLuca, H.F. Deposit date: 2006-12-04 Release date: 2007-01-30 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.74 Å) Cite: New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D(3) with conformationally restricted side chains: Evaluation of biological activity and structural determination of VDR-bound conformations. Arch.Biochem.Biophys., 460, 2007
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2006-12-04
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