FGF2 effects on the transcriptome of the human dermal fibroblasts
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https://www.ncbi.nlm.nih.gov/sra/SRP279219
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资源简介：
The current study was to determine the effects of Fibroblast Growth Factor 2 (FGF2) on the transcriptome of adult human dermal fibroblasts. Transcriptional profiles of adult human dermal fibroblasts grown in culture medium (with FGF2 or not) were compared. Comparison of the transcriptomes will allow to identify significantly differentially expressed genes exposure to FGF2, which in turn will allow for identification of the pathways affected by these factors in the human adult fibroblasts. Methods: Human dermal fibroblasts were FGF2 (10ng/ML) treatment for 48h hours. Then, the RNA was extracted for library construction Results: FGF2-responsive genes were significantly involved in ECM-receptor interaction, PI3K-Akt signaling and Hippo pathway. Overall design: RNA profiles of FGF2-treated human dermal fibroblasts were generated by sequencing.
创建时间：
2021-02-07
