Known diagnostic protein biomarkers were significantly enriched in the sets of differentially expressed RNA for 22 out of 41 diseases.
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https://figshare.com/articles/dataset/_Known_diagnostic_protein_biomarkers_were_significantly_enriched_in_the_sets_of_differentially_expressed_RNA_for_22_out_of_41_diseases_/499546
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*Number of genes that were differentially expressed in any one of the disease tissues at the mRNA level (fpf≤0.05, RankProd R package) with detectable protein abundance in the biofluid proteome database (see Methods).
*Number of known diagnostic protein biomarkers in clinical and preclinical studies from the GVK BIO Online Biomarker Database (GOBIOM).
**Number of correctly predicted diagnostic protein biomarkers.
$P values were calculated to evaluate whether known protein biomarkers were significantly enriched in our predicted genes using Fisher's exact test.
创建时间：
2010-09-23
