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A Convergent Synthesis of the Fully Elaborated Macrocyclic Core of TMC-95A

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Figshare2016-02-18 更新2026-04-29 收录
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https://figshare.com/articles/dataset/A_Convergent_Synthesis_of_the_Fully_Elaborated_Macrocyclic_Core_of_TMC_95A/2316961
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A concise and straightforward synthesis of the fully elaborated macrocyclic core of TMC-95A is reported. A highly efficient organocatalyzed aldolization between isatin and dihy­droxy­acetone derivatives and formation of the biaryl subunit with concomitant macrocyclization are the characteristic features of this synthesis.
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2016-02-18
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