Expression data from mouse bone marrow adipocytes with age

The aim of this study was to characterize the age-related gene expression profiles between bone marrow adipocytes and peripheral white adipocytes. Alterations of gene expression with aging were analyzed in bone marrow and peripheral white adipocytes isolated from C57BL/6J male mice using Affymetrix Mouse Gene 1.0 ST arrays. Bone marrow adipocytes and peripheral white adipocytes (n=6-10 animals per group) were isolated from male C57BL/6J mice (6-months, 14-months and 18-months of age). Samples were grouped into cell type (bone marrow adipocytes vs. peripheral adipocytes) and age (6-month (6M), 14-month (14M) and 18-month (18M)).本研究旨在解析骨髓脂肪细胞与外周白色脂肪细胞之间的年龄相关基因表达谱。研究采用Affymetrix小鼠基因1.0 ST芯片（Affymetrix Mouse Gene 1.0 ST arrays），对从C57BL/6J雄性小鼠中分离得到的骨髓脂肪细胞与外周白色脂肪细胞的衰老相关基因表达变化进行分析。实验每组使用6-10只动物，分别从6月龄、14月龄及18月龄的雄性C57BL/6J小鼠体内分离骨髓脂肪细胞与外周白色脂肪细胞。最终样本按细胞类型（骨髓脂肪细胞 vs 外周脂肪细胞）与年龄（6月龄（6M）、14月龄（14M）及18月龄（18M））进行分组。