A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures
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A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures Descriptor: 1-hexadecyl-2-methyl-3-(phenylmethyl)imidazol-3-ium, Alpha-(1,6)-fucosyltransferase Authors: Jiang, J, Fang, P. Deposit date: 2024-12-24 Release date: 2026-01-07 Last modified: 2026-04-01 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Exploiting human fucosyltransferase 8 allostery with a covalent inhibitor for core fucosylation suppression. Nat Commun, 17, 2026
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2024-12-24
