Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 8-methyl UAB30 and the coactivator peptide GRIP-1
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 8-methyl UAB30 and the coactivator peptide GRIP-1 Descriptor: (2E,4E,6Z,8E)-3,7-dimethyl-8-(8-methyl-3,4-dihydronaphthalen-1(2H)-ylidene)octa-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha Authors: Xia, G, Smith, C.D, Muccio, D.D. Deposit date: 2014-02-25 Release date: 2014-06-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Methyl substitution of a rexinoid agonist improves potency and reveals site of lipid toxicity. J.Med.Chem., 57, 2014
创建时间：
2014-02-25
