首页/数据集/Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD

Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD

NIAID Data Ecosystem2026-03-13 收录

额颞叶痴呆

细胞疾病模型

数据链接：

https://www.omicsdi.org/dataset/ega/EGAS00001006138 数据链接链接失效反馈

官方服务：

资源简介：

To investigate the mode of action and potential side-effects we analyzed differential gene expression in post-mitotic C9orf72 iPSC-Neurons by RNAseqEGA study EGAS00001006138

应用场景：

创建时间：

2022-06-08

额颞叶痴呆

认知功能障碍

Background: The cognitive and neuropsychiatric deficits present in patients with behavioral variant frontotemporal dementia (bvFTD) are associated with loss of functionality in the activities of daily

NIAID Data Ecosystem650

Metadata record for: MNI-FTD Templates, unbiased average templates of frontotemporal dementia variants

额颞叶痴呆

脑模板构建

This dataset contains key characteristics about the data described in the Data Descriptor MNI-FTD Templates, unbiased average templates of frontotemporal dementia variants. Contents: 1. huma

Figshare2021-08-19 更新60

Data_Sheet_3_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.PDF

神经退行性疾病

细胞疾病模型

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by gradual degeneration and elimination of motor neurons (MNs) in the motor cortex, brainstem, and spinal cord.

NIAID Data Ecosystem40

RNA-seq in healthy and SQT1 hiPSC-CMs upon manipulation of miR-365

心脏电生理调控

细胞疾病模型

Abnormalities of ventricular action potential (AP) cause malignant cardiac arrhythmias and sudden cardiac death. Here, we sought to identify microRNAs (miRNAs) that regulate the human cardiac AP and a

NIAID Data Ecosystem80

Characterizing the clinical features and atrophy patterns of MAPT-related frontotemporal dementia with disease progression modelling (Supplementary Data)

额颞叶痴呆

医学影像分析

Background and Objective: Mutations in the MAPT gene cause frontotemporal dementia (FTD). Most previous studies investigating the neuroanatomical signature of MAPT mutations have grouped all different

NIAID Data Ecosystem50

Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD

资源简介：

相关数据集