All miRNAs that showed some alteration in at least one stage of sleeping sickness are shown. Log2 FC is Log2 of the arithmetic mean fold change in patients relative to the average value for controls.
In order to test the differences of miRNA expression between plasma microvesicles and PBMC, data were analyzed using linear mixed models. The p-values were generated from the model based on the estima
ImportanceEpigenetic modifications of the genome, such as DNA methylation and histone modifications, have been reported to play a role in neurodegenerative diseases (ND) such as Alzheimer’s disease (A