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Expression data of KDM4C knockout by CRISPR in Prostate cancer cell line C4-2B. Expression data of KDM4C knockout by CRISPR in Prostate cancer cell line C4-2B

NIAID Data Ecosystem2026-03-12 收录

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表观遗传基因功能

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA740242 数据链接链接失效反馈

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资源简介：

Histone Demethylase KDM4C promotes prostate cancer metastasis via induction of c-Myc and LDHA Overall design: Triplicates test of control samples and CRISPR knockout KDM4C samples in the study

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创建时间：

2021-06-23

外泌体miRNA分析

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Background: Androgen deprivation therapy (ADT) is the backbone of therapy for advanced prostate cancer (PCa). Despite the good initial response, castration resistance and metastatic progression will i

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Targeting PRC1 Suppresses Double Negative Prostate Cancer Metastasis by Inhibiting Stemness and Reversing Immune Suppression

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肿瘤免疫微环境

The mechanisms that enable immune evasion at metastatic sites are poorly understood. We show that the Polycomb Repressor Complex-1 drives the colonization of the bones and visceral organs in Double-Ne

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The evolutionary steps from primary to metastatic prostate cancer are largely uncharted, and the ability to use DNA present in body fluids as correlates of aggregate metastatic status is under-examined. We reconstructed phylogenies in ten prostate cancer patients with fatal disease using deep targeted sequencing of the prostate, adjacent and distant organs, as well as plasma, serum, and cerebrospinal fluid at various time points. A total of 163 samples are studied.

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肿瘤克隆动态

The evolutionary steps from primary tumor to metastasis in prostate cancer are largely uncharted, and the ability to use serum, plasma, and cerebrospinal fluid as a correlate of aggregate metastatic t

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Expression profile of PC-3-derived cell lines after transendothelial migration

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跨内皮迁移

Metastatic colonization involves cancer cell lodgment or adherence in the microvasculature and subsequent migration of those cells across the endothelium into a secondary organ site. To study this pr

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Knockdown of Akt1/2 by CRISPR/Cas9 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo. Knockdown of Akt1/2 by CRISPR/Cas9 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo

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CRISPRi基因编辑

Our findings will initially map out the downstream signal pathways of Akt and AR mutual feedback to regulate CaP metastasis through the study of these scientific assumptions, which will provide target

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Expression data of KDM4C knockout by CRISPR in Prostate cancer cell line C4-2B. Expression data of KDM4C knockout by CRISPR in Prostate cancer cell line C4-2B

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