Next Generation Sequencing Facilitates Quantitative Analysis of CAFR and CAFS Transcriptomes in pancreatic cancer

We extracted primary CAFs from the tumor tissue of chemoresistant and chemosensitive pancreatic cancer patients (namely CAFR and CAFS). The Goal of this study is to compare the transcriptomes difference between CAFR and CAFS. And we come to a conclusion that CAFR is possessed of a iCAF phenotype. Overall design: mRNA profiles of CAFR and CAFS.