five

Mafb lineage tracing marks macrophages

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE86596
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Current systems for conditional gene deletion within mouse macrophage lineages are limited by ectopic activity or low efficiency; we generated a Mafb-driven Cre strain to determine whether any dendritic cells (DCs) identified by Zbtb46-GFP expression originate from a Mafb-expressing population Ly-6C(hi) monocytes, Ly-6C(lo) YFP(-) monocytes, and Ly-6C(lo) YFP(+) monocytes were isolated by FACS from blood samples harvested from MafB-mCherry-Cre x R26-stop-YFP x Zbtb46-GFP lineage-tracing mice
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2019-03-04
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