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Imbalanced TGF-beta signalling and autophagy drive erythroid priming of hematopoietic stem cells in Beta-thalassemia

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP499953
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We evaluated how the disease impacts the gene expression within hematopoietic stem cells and progenitors Overall design: To profile transcriptional differences between Bthal and HD primitive hematopoietic cells, we performed RNAseq on different hematopoietic subpopulations isolated by Fluorecence-activated cell sorting (FACS) from Bthal and healthy donor (HD) bone marrow CD34+ cells .
创建时间:
2025-07-11
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