Novel Synthesis of Right Segment of Solanoeclepin A
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The highly strained tricyclo[5.2.1.01,6]decene skeleton of solanoeclepin A was synthesized through two key C–C bond forming processes; thus, a Hg(TFA)2-mediated oxymercuration followed an intramolecular aldol reaction to B and a SmI2-mediated cyclization of C between an aldehyde and an unsaturated ester to form the cyclobutane D having a tricyclo[5.2.1.01,6]dodecene.
创建时间:
2016-02-17



