Characterization of changes in expression levels during infections with Japanese encephalitis virus in search of pathways affected during the course of the infection. Identification of affected pathwa
Background Japanese encephalitis (JE) virus (JEV) is a mosquito-borne flavivirus found across Asia that is closely related to West Nile virus. There is no known antiviral treatment for any flavivirus.
Additional file 4: Fig. S2. Volcano plot of global DEGs at different time points. V P3 vs. Mock 12 h (A), JEV P3 vs. Mock 36 h (B), JEV P3 vs. Mock 72 h (C). Purple dots (right) and red dots (left) re
Controlling the proinflammatory response of microglia by targeting chemokines (C-C motif) receptor 2 (CCR2) could be an important therapeutic approach for Japanese encephalitis virus (JEV) infection.