Results of discovery stage, replication stage and the overall meta-analysis of the 25 SNPs associated with RMSSD (p<0.05) in the discovery stage.

SNPs are sorted according to p-value in the discovery cohort.Note: RMSSD was log-transformed prior data analysis. Analyses are age & sex adjusted. Discovery stage sample size (N) = 3429; Replication stage N = 3311(except for one SNP [rs333214] in the SLC5A7 gene where N = 516, because this SNP could not be analyzed in PREVEND due to low imputation quality); and overall meta-analysis N = 6740. See the methods section for further details on the imputation procedures for the different cohorts. C/NC, coded/non-coded allele; CAF, coded allele frequency.Results of discovery stage, replication stage and the overall meta-analysis of the 25 SNPs associated with RMSSD (p