Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors

Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors Descriptor: 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol, Glycogen synthase kinase-3 beta peptide, RAC-beta serine/threonine-protein kinase Authors: Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P. Deposit date: 2008-08-19 Release date: 2008-10-14 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Aminofurazans as potent inhibitors of AKT kinase Bioorg.Med.Chem.Lett., 19, 2009